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2019 December 09

MS

Maxim Sysoev in Science FYI
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AZ

Arthur Zalevsky in Science FYI
вот уж внезапность то
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AG

Azamat Gafurov in Science FYI
Gav
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G

German in Science FYI
Вот ща тупой вопрос будет: а когда трансплантацию костного мозга делают, на иммуносупрессорах надо сидеть пока полностью имунные клетки не сменятся?
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G

German in Science FYI
Нашол, на вики неплохо написано
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b

brnr in Science FYI
А вот и ответ на мой вопрос
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G

German in Science FYI
Вообще говоря это шляпа какая то, а не статья
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G

German in Science FYI
"But four years after his lifesaving procedure, it was not only Long’s blood that was affected. Swabs of his lips and cheeks contained his DNA – but also that of his donor. Even more surprising to Long and other colleagues at the crime lab, all of the DNA in his semen belonged to his donor. “I thought that it was pretty incredible that I can disappear and someone else can appear,” he said."
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G

German in Science FYI
Это полная чушь
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G

German in Science FYI
Или нет?
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b

brnr in Science FYI
Телегония какая-то
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MS

Maxim Sysoev in Science FYI
Let's be clear, this does not mean this man will be having children with his donor's DNA, as many people seem to be thinking.

The article says all of the DNA in his semen belongs to his donor, it does not say sperm. This man has had both high dose chemotherapy and a vasectomy, making this man's chances of having any actual sperm in his semen almost zero. What must also be recognized is that semen contains more cells than just sperm. It seems the most common type of cells, beyond sperm cells, found in semen are white blood cells. These of course would have the donor's DNA given that was the point of the transplant. So if the lab is collecting a normal semen sample from this man, this might actually be the expected result and not something super novel, just maybe no one had thought about it or actually tested it before.

So does this have implication for crimes, sure. Does this mean the man is now producing donor sperm cells and will be having children with his donor's DNA, no.
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2019 December 10

DP

Defragmented Panda in Science FYI
Время делать трансплантацию яичек. Хотя бы просто потролить общественность.
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EL

Eka L in Science FYI
Коллеги со степенью, кому интересно:
https://www.imb.de/students-postdocs/imb-postdoc-programme
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EL

Eka L in Science FYI
Регистрация до 9 января.
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M

MT in Science FYI
German
"But four years after his lifesaving procedure, it was not only Long’s blood that was affected. Swabs of his lips and cheeks contained his DNA – but also that of his donor. Even more surprising to Long and other colleagues at the crime lab, all of the DNA in his semen belonged to his donor. “I thought that it was pretty incredible that I can disappear and someone else can appear,” he said."
Хихикаю
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M

MT in Science FYI
Maxim Sysoev
Let's be clear, this does not mean this man will be having children with his donor's DNA, as many people seem to be thinking.

The article says all of the DNA in his semen belongs to his donor, it does not say sperm. This man has had both high dose chemotherapy and a vasectomy, making this man's chances of having any actual sperm in his semen almost zero. What must also be recognized is that semen contains more cells than just sperm. It seems the most common type of cells, beyond sperm cells, found in semen are white blood cells. These of course would have the donor's DNA given that was the point of the transplant. So if the lab is collecting a normal semen sample from this man, this might actually be the expected result and not something super novel, just maybe no one had thought about it or actually tested it before.

So does this have implication for crimes, sure. Does this mean the man is now producing donor sperm cells and will be having children with his donor's DNA, no.
>This man has had both high dose chemotherapy and a vasectomy

Герой нашего времени
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AZ

Arthur Zalevsky in Science FYI
German
Или нет?
дай угадаю, соскобы эпителия содержат примесь клеток крови?)
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AZ

Arthur Zalevsky in Science FYI
и вообще, мозаицизм и прочие подобные артефакты в генетическом анализе — популярная вещь)
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G

German in Science FYI
Ну да, но обычно ж мозаицизм в небольшой части клеток ну или очень локально, и все таки происходит чаще из за мутаций в эмбриональном развитии, поэтому скажем целая область ему подвержена. Это я про то что мозаицизм обычно и не видно ни на каких днк анализах потому что клональность маленькая
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