Open Targets is a public-private initiative to generate evidence on the validity of therapeutic targets based on genome-scale experiments and analysis.

Gesine Dreisbach We always hesitate to call retraction statements “models” of anything, but this one comes pretty close to being a paragon.  Psychology researchers in Germany and Scotland have…

A comprehensive list of candidate genes that succinctly describe the complete and objective phenotypic features of disease is critical when both ordering genetic testing and when triaging candidate variants in exome and genome sequencing studies. Great efforts have been made to curate gene:disease associations both in academic research and commercial gene testing settings. However, many of these valuable resources exist as islands and must be used independently, generating static, single-resource gene:disease association lists. To more effectively utilize these resources we created genepanel.iobio (<https://genepanel.iobio.io>), an easy to use, free and open-source web tool for generating disease- and phenotype-associated gene lists from multiple gene:disease association resources, including the NCBI Genetic Testing Registry (GTR), Phenolyzer, and the Human Phenotype Ontology (HPO). We demonstrate the utility of genepanel.iobio by applying it to complex, rare and undiagnosed disease cases which had reached a…

Министерство высшего образования и науки в июле разослало в подведомственные организации рекомендации по контактам с иностранными и международными организациями и приему иностранных граждан.